MD Breaking News

Low Testosterone May Be Risk Factor for COVID-19 Hospitalization in Men

A new study published September 2, 2022 in the prestigious journal JAMA Network Open “suggests that men with hypogonadism were more likely to be hospitalized after COVID-19.”

MedicalXpress further reported on September 2, 2022 it was that in “men diagnosed with COVID-19, those with low testosterone levels are more likely to become seriously ill and end up in the hospital than men with normal levels of the hormone,” according to a study by researchers at Washington University School of Medicine and Saint Louis and Saint Louis University School of Medicine.

The researchers “found that men with low testosterone who developed COVID-19 were 2.4 times likely to require hospitalization than men with hormone levels in the normal range. Further, men who were once diagnosed with low testosterone but successfully treated with hormone replacement therapy were no more likely to be hospitalized for COVID-19 than men whose testosterone levels had always tested in the normal range.”

The researchers acknowledged that “low testosterone turned out to be risk factor for hospitalizations from COVID, and treatment of low testosterone help to negate the risk,” according to co-senior author Sandeep Dhindsa, MD an endocrinologist at Saint Louis University. “The risk really takes off below a level of 200 nanograms per deciliter, with the normal range being 300 to 1,000 nanograms per deciliter. This is independent of all other risk factors that we looked at: age obesity or other health conditions. But those people who were on therapy, their risk was normal.”


1. Dhindsa S, Champion C, Deol E, et al. Association of Male Hypogonadism With Risk of Hospitalization for COVID-19. JAMA Network Open, Sept 2, 2022;5(9):e2229747. doi:10.1001/jamanetworkopen.2022.29747

2. Low testosterone may increase risk of COVID-19 hospitalization for men by Washington University School of Medicine. September 2, 2022. MedicalXpress

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