The nucleus is the center for protein synthesis in cells throughout the body. Skeletal muscle cells are unique because they contain more than one nucleus. Muscle cells increase cell nuclei by generating satellite cells in response to cell damage and muscle tension caused by weight training. This increases the capacity for muscle hypertrophy in the future and helps trained muscles maintain increased size.
Danish researchers found that intense training with light loads increased satellite cells as well as heavier loads. This study showed that increasing muscle size is possible with a variety of training approaches. A basic principle of sports training is that almost everything works to an extent. This explains why athletes achieve success with a variety of training methods. (Scandinavian Journal Medicine Science Sports, published online)